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July 1, 1978AJP Regulatory Integrative and Comparative Physiology16 citations

Calibrating compartmental models of neurons

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DPDonald H. PerkelRAND CorporationBMBrian MulloneyUniversity of California, Davis

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Abstract

Numerical parameters for a compartmental model of a neuron can be chosen to conform both to the neuron's structure and to its measured steady-state electrical properties. A systematic procedure for assigning parameters is described that makes use of the matrix of coefficients of the set of differential equations that embodies the compartmental model. The inverse of this matrix furnishes input resistances and voltage attenuation factors for the model, and an interactive modification of the original matrix and its inverse may be used to fit the model to anatomic and electrical measurements.

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Cite This Study

Perkel et al. (1978) studied this question.

synapsesocial.com/papers/6a185026a61bfdbaa2c97dc3https://doi.org/10.1152/ajpregu.1978.235.1.r93
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