Key result
Urgent CABG in ACS patients had similar 30-day survival (p=0.056) but increased postoperative myocardial infarction (p=0.02) and prolonged hospital stay (p<0.001) compared to elective CABG.
Why the study?
Does urgent CABG increase postoperative complications compared to elective CABG in patients with acute coronary syndrome?
Cohort (n=100)
Does urgent CABG increase postoperative complications compared to elective CABG in patients with acute coronary syndrome?
In patients with ACS, urgent CABG increases the risk of postoperative MI and prolongs hospital stay compared to elective CABG, though 30-day survival rates are similar.
Answers are grounded in this paper and cite their sources.
May increase postoperative MI and hospital stay after urgent CABG in ACS; leaves open optimal timing in prospective trials.
In this retrospective study, we aimed to evaluate the clinical outcomes, risk factors of mortality and prognosis after urgent coronary artery bypass grafting (CABG) in acute coronary syndrome (ACS) patients. Our study included 100 patients who underwent CABG for ACS (50 urgent and 50 elective). All patients were followed for 30 days after surgery, both clinically and echocardiographically. Data were analyzed using the SPSS software in accordance to the Society of Thoracic Surgeons (STS) National Cardiac Surgery Database guidelines. Patients in the urgent CABG group were of younger age (p = .03) and had a higher frequency of smoking (p = .04) and dyslipidemia (p = .004); otherwise, all baseline characteristics were comparable between the two groups. The cardiopulmonary bypass (CPB) (p = .003) and aortic cross-clamp times (p = .02) were significantly longer in the urgent CABG group compared to the elective CABG group. Although both groups had a relatively similar survival rate (p = .056), urgent CABG patients were more liable to postoperative myocardial infarction (p = .02), as well as prolonged ventilation time (p = .002) and hospital stay (p < .001). Our analysis showed that preoperative low ejection fraction (EF) (p = .03), use of inotropes (p = .002) and prolonged CPB time (p = .04) were independent risk factors for mortality after urgent CABG. Urgent CABG increased the risk of myocardial infarction and prolonged hospital stay in comparison to elective CABG. Moreover, preoperative low EF and prolonged CPB time were associated with a significant increase in the risk of mortality after urgent CABG.
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Mohammad et al. (2018) conducted a cohort in Acute coronary syndrome (ACS) (n=100). Urgent CABG vs. Elective CABG was evaluated on Survival rate (p=0.056). Urgent CABG in ACS patients had similar 30-day survival (p=0.056) but increased postoperative myocardial infarction (p=0.02) and prolonged hospital stay (p<0.001) compared to elective CABG.
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