Cardiac magnetic resonance imaging detected late gadolinium enhancement in 45% of idiopathic dilated cardiomyopathy patients and correlated with 2D echocardiography for LV ejection fraction (P=0.442).
Observational (n=40)
No
Does cardiac magnetic resonance imaging accurately characterize late gadolinium enhancement and correlate with echocardiography for LV function assessment in patients with idiopathic dilated cardiomyopathy?
CMR effectively identifies the presence, location, and pattern of LGE in idiopathic dilated cardiomyopathy and correlates with echocardiography for assessing LV ejection fraction.
p-value: p=0.442
Purpose: The present study was aimed to assess the prevalence, location, and patterns of late gadolinium enhancement (LGE) in idiopathic dilated cardiomyopathy (DCM) on cardiac magnetic resonance (CMR) imaging and to correlate the left ventricular (LV) functions obtained by cine CMR with the values obtained by echocardiography. Methods: This was a prospective single-center study covering a 2-year study period. The authors studied the prevalence, location, and patterns of LGE in idiopathic DCM on CMR and correlated the ventricular functions obtained by CMR with those obtained by echocardiography. Results: LGE was seen in 18/40 (45%) and was absent in 22/40 (55%) of patients. With regard to location, septal enhancement was the most common, seen in 8 (20%) followed by free-wall enhancement in 4 (10%) and a concomitant septal and free-wall enhancement in 6 (15%). In terms of pattern, midwall enhancement was observed in 10 (25%), subepicardial in 2 (5%), subendocardial in 4 (10%), and focal and transmural enhancement in 1 each. The maximum correlation for calculation of LV ejection fraction (EF) was obtained between CMR and two-dimensional echocardiography ( P = 0.442). Conclusion: CMR is an accurate tool to determine the phenotype of DCM by identifying the presence, location, and pattern of LGE which has a prognostic value and is used to guide management. CMR is the most accurate assessment tool for the calculation of EF and other volumetric variables in DCM.
Khan et al. (Fri,) conducted a observational in Idiopathic dilated cardiomyopathy (DCM) (n=40). Cardiac magnetic resonance (CMR) imaging vs. Two-dimensional echocardiography was evaluated on Prevalence, location, and patterns of late gadolinium enhancement (LGE) and correlation of LV ejection fraction (p=0.442). Cardiac magnetic resonance imaging detected late gadolinium enhancement in 45% of idiopathic dilated cardiomyopathy patients and correlated with 2D echocardiography for LV ejection fraction (P=0.442).