Key result
Disopyramide achieved a 60% reduction in resting outflow tract gradient by mitigating intracellular Ca2+ levels without directly affecting the contractile apparatus.
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Martin S. Maron (2019) conducted an editorial in Hypertrophic Cardiomyopathy (HCM) (n=39). Disopyramide vs. Baseline (before therapy) was evaluated on Resting outflow tract gradient. Disopyramide achieved a 60% reduction in resting outflow tract gradient by mitigating intracellular Ca2+ levels without directly affecting the contractile apparatus.
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