Key result
Recalibrated AMI model predicts extended hospital stay with ~0.75 AUC, driven primarily by cardiogenic shock.
Why the study?
Cardiovascular diseases significantly impact hospital length of stay, and this study aimed to validate and recalibrate a predictive model for extended length of stay in patients admitted with acute myocardial infarction.
Observational (n=1,531)
No
Absolute Event Rate: 0.745% vs 0.702%
A recalibrated predictive model successfully identified patients with acute myocardial infarction at high risk for extended hospital length of stay using admission comorbidities and laboratory data.
May aid risk stratification for prolonged AMI stay; hypothesis-generating and requires prospective validation before clinical use.
Background: Cardiovascular diseases are still a significant cause of death and hospitalization. In 2019, circulatory diseases were responsible for 29.9% of deaths in Portugal. These diseases have a significant impact on the hospital length of stay. Length of stay predictive models is an efficient way to aid decision-making in health. This study aimed to validate a predictive model on the extended length of stay in patients with acute myocardial infarction at the time of admission. Methods: An analysis was conducted to test and recalibrate a previously developed model in the prediction of prolonged length of stay, for a new set of population. The study was conducted based on administrative and laboratory data of patients admitted for acute myocardial infarction events from a public hospital in Portugal from 2013 to 2015. Results: Comparable performance measures were observed upon the validation and recalibration of the predictive model of extended length of stay. Comorbidities such as shock, diabetes with complications, dysrhythmia, pulmonary edema, and respiratory infections were the common variables found between the previous model and the validated and recalibrated model for acute myocardial infarction. Conclusion: Predictive models for the extended length of stay can be applied in clinical practice since they are recalibrated and modeled to the relevant population characteristics.
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Xavier et al. (2023) conducted an observational in Acute myocardial infarction (AMI) (n=1,531). Recalibrated predictive model (RM) vs. Validation model (VM) was evaluated on Discriminatory capacity (AUC) for predicting extended length of stay. A recalibrated predictive model for extended hospital length of stay in patients with acute myocardial infarction achieved an AUC of 0.745, with cardiogenic shock being the strongest predictor (OR 22.96).
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