Key result
Carotid artery stenting shows a ~6% 1-year complication rate, driven primarily by stent thrombosis.
Why the study?
The study aimed to examine complications occurring after carotid artery stenting and their relationships with the carotid artery stenosis rate.
Observational (n=195)
No
Carotid artery stenting has an acceptable overall complication rate, but the risk of complications, particularly stent thrombosis and occlusion, is notably higher in symptomatic patients, emergency cases, and those with ≥90% stenosis.
Objective: This study aimed to examine complications that may occur after carotid artery stenting (CAS) and their relationships with carotid artery stenosis rate. Materials and Methods: Complications, such as cerebral hyperperfusion, stroke, death, stent thrombosis or occlusion and restenosis, were evaluated on the 30th day after CAS and at the end of the first year. Results: Of the 205 CAS procedures, complications developed in 12 patients. The complication rate for the first 30 days after the procedure was 4,87%, and at the end of the first year, it was 5,85%. Of the 12 patients with complications, 8 had carotid stenosis of ≥90%. Death occurred in 4 of 195 patients with carotid artery stenosis. The mortality rate within the first 30 days and during the 1-year follow-up period was 1,53% and 2,05%, respectively. Ischemic stroke occurred in 6 of 195 patients with carotid artery stenosis. After the first 30 days and one year follow-up, ischemic stroke had occurred in 3,07% of patients. Stent thrombosis and occlusion rate was 4,87% in 205 CAS procedures, and 7 of them occurred in the first 24 hours and another 3 occurred within the first 30 days. Restenosis rates were 0,48% and 0,97% at 6 months and the first year, respectively. Conclusion: The complications of CAS have been associated with the urgency of treatment (emergency), symptom presence (symptomatic patients) and high degree of stenosis (≥90%); whereas bilateral stenosis is not associated with complications. In addition, stent thrombosis and occlusion were observed as the most common CAS complication.
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Deniz et al. (2023) conducted an observational in Extracranial carotid artery stenosis (n=195). Carotid artery stenting (CAS) was evaluated on Overall complication rate (stroke, death, restenosis, cerebral hyperperfusion, stent thrombosis/occlusion) at 1 year. Carotid artery stenting resulted in a 1-year complication rate of 5.85%, with stent thrombosis/occlusion being the most common complication, particularly in symptomatic patients or those with ≥90% stenosis.
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