This review discusses recent advances in the pathology, diagnosis, and management of unstable angina and non-ST elevation myocardial infarction, including biomarkers and antiplatelet therapy.
This review provides a comprehensive overview of advances in the understanding and management of unstable angina and NSTEMI, highlighting the roles of inflammation, biomarkers, and interventional strategies.
Within the coronary vasculature the progression of a stable atherosclerotic plaque into a vulnerable and ultimately unstable lesion leads to a cascade of events culminating in the clinical presentation of unstable angina or acute myocardial infarction. In recent years studies have provided new insights in to the pathology and natural history, stimulating advances in diagnosis, treatment, and management. The review discusses the progress made including the role of inflammation, cardiac biomarkers, antiplatelet therapy, and percutaneous intervention. Current issues of debate and future directions are also addressed.
Sheridan et al. (Sun,) conducted a review in Unstable angina and non-ST elevation myocardial infarction. This review discusses recent advances in the pathology, diagnosis, and management of unstable angina and non-ST elevation myocardial infarction, including biomarkers and antiplatelet therapy.