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DNA-dependent RNA polymerase I was purified from the mouse myeloma, MOPC 315.The enzyme was solubilized from purified nucleoli and subjected to chromatography on CM-Sephadex, DEAE-Sephadex, and phosphocellulose ion exchange resins and to sedimentation in sucrose gradients.
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Schwartz et al. (1974) studied this question.
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