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May 29, 2026Clinics and PracticeOpen Access

Segmental Arterial Mediolysis Associated with Renal Allograft Artery Dissection and Thrombosis During Kidney Transplantation

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Authors

MZMatteo ZanchettaNCNatale CalominoGIGiuseppe Ietto

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Overview

Case report reveals catastrophic arterial thrombosis during kidney transplantation, suggesting need for awareness of segmental arterial mediolysis.

Key Points

  • This case report aims to highlight the occurrence of segmental arterial mediolysis in a renal allograft during transplantation, questioning the mechanisms behind early graft failure.
  • Presentation of a kidney graft from a deceased donor transplanted into a recipient
  • Assessment of immunological compatibility, ischemia times, and intraoperative flow measurements
  • Histopathological examination of graft arterial tissue following observed thrombosis
  • Thrombosis of the graft renal artery occurred immediately after declamping despite surgical intervention.
  • Histopathological findings indicated characteristics of segmental arterial mediolysis, including arterial dissection and occlusive thrombosis.
  • The graft was ultimately explanted and deemed unsalvageable.

Cite This Study

Zanchetta et al. (2026) studied this question.

synapsesocial.com/papers/6a192d13fab5b468c4415e7ehttps://doi.org/10.3390/clinpract16060099
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