Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction | Synapse
May 29, 2026
Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction
Key Points
This research aims to develop a one-pot deracemization method for aryl-ring-containing secondary alcohols.
Utilized a dual biocatalytic system involving an unspecific peroxygenase and an alcohol dehydrogenase.
Performed the deracemization in a one-pot, two-step process.
Achieved effective conversion of secondary alcohols using the dual biocatalytic approach.
Demonstrated potential for enhanced efficiency in synthetic applications.
Abstract
We report a one-pot two-step deracemization strategy for aryl-ring-containing secondary alcohols using a dual biocatalytic system that combines an unspecific peroxygenase and an alcohol dehydrogenase.