Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction

Hebah Abuzenah; Jabir Khan; Frank Hollmann; Masateru Takahashi; Etsuko Takahashi; Samir M. Hamdan; Musa Musa

doi:10.1039/d6nj01585a

January 1, 2026New Journal of Chemistry

Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction

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Key Points

This research aims to develop a one-pot deracemization method for aryl-ring-containing secondary alcohols.
Utilized a dual biocatalytic system involving an unspecific peroxygenase and an alcohol dehydrogenase.
Performed the deracemization in a one-pot, two-step process.
Achieved effective conversion of secondary alcohols using the dual biocatalytic approach.
Demonstrated potential for enhanced efficiency in synthetic applications.

Implication

Explores deracemization of secondary alcohols, suggesting effective biocatalytic methods.

Abstract

We report a one-pot two-step deracemization strategy for aryl-ring-containing secondary alcohols using a dual biocatalytic system that combines an unspecific peroxygenase and an alcohol dehydrogenase.

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Cite This Study

Abuzenah et al. (2026) studied this question.

synapsesocial.com/papers/6a192d2efab5b468c4416042 https://doi.org/10.1039/d6nj01585a

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Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction

Key Points

Implication

Abstract

Discussion

Cite This Study

Dual biocatalytic one-pot deracemization of aryl-ring-containing secondary alcohols via sequential oxidation–reduction

Key Points

Implication

Abstract

Discussion

Cite This Study

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