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Case report reveals vitamin C deficiency causes reversible pulmonary arterial hypertension in a child with autism, highlighting dietary concerns.
Learning Points Pulmonary arterial hypertension (PAH) is a rare, serious, and reversible complication of vitamin C deficiency in children. Vitamin C deficiency, amongst other micronutrient deficiencies, is common in children with ASD due to restrictive dietary intake. In cases of PAH of unknown cause in paediatric patients, serum vitamin C testing should be considered, with vitamin C supplementation as indicated.
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Redwood et al. (2026) studied this question.
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