Demonstrates efficient trifluoromethylation in enamines, implying new synthesis techniques.
An efficient β-trifluoromethylation and perfluoroalkylation of enamide derivatives has been achieved under mild, transition metal-free conditions without requiring oxidants or photocatalysts. Using trifluoromethyl or perfluoroalkyl iodides via an aryl radical-mediated...
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Chen et al. (2026) studied this question.
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