Clicking the sustainability: Nobel-awarded copper catalysed azide-alkyne cycloadditions (CuAAC) through Life Cycle Assessments analysis

Luigi Vaccaro; Filippo Campana; Daniela Lanari

doi:10.1039/d6gc01508e

January 1, 2026Green ChemistryOpen Access

Clicking the sustainability: Nobel-awarded copper catalysed azide-alkyne cycloadditions (CuAAC) through Life Cycle Assessments analysis

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Key Points

The aim is to evaluate the sustainability of copper-catalyzed azide-alkyne cycloadditions (CuAAC) through life cycle assessments.
Conducted life cycle assessments to analyze the environmental impact of CuAAC processes.
Evaluated various copper catalysts and their effectiveness in these reactions.
Identified significant environmental benefits associated with CuAAC over other chemical methods.
Found lower resource consumption and byproduct generation in copper-catalyzed processes.

Implication

Analyzes the sustainability of CuAAC reactions, suggesting improved environmental impact.

Abstract

Copper-catalyzed azide-alkyne cycloadditions represent a class of chemical reactions belonging to the broader group of socalled "click reactions." In this context, the copper-catalyzed azide-alkyne cycloaddition (CuAAC), which contributed to Sharpless...

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Cite This Study

Vaccaro et al. (2026) studied this question.

synapsesocial.com/papers/6a192dbbfab5b468c44169bf https://doi.org/10.1039/d6gc01508e

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Clicking the sustainability: Nobel-awarded copper catalysed azide-alkyne cycloadditions (CuAAC) through Life Cycle Assessments analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Clicking the sustainability: Nobel-awarded copper catalysed azide-alkyne cycloadditions (CuAAC) through Life Cycle Assessments analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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