Evaluation of the Forced Inspiratory Suction and Swallow Tool for Chemotherapy-Induced Hiccups

BACKGROUND: Chemotherapy-induced hiccups (CIH) impair quality of life in patients with cancer, yet effective nonpharmacological management is limited. The Forced Inspiratory Suction and Swallow Tool (FISST) has shown efficacy in healthy individuals. OBJECTIVES: This study aimed to evaluate the usefulness of the FISST for chemotherapy-induced hiccups (CIH). DESIGN: This was a prospective observational study. SETTING/SUBJECTS: This study enrolled 44 hospitalized patients receiving chemotherapy at a single center in Japan; patients who developed hiccups during hospitalization were included in the analysis. MEASUREMENTS: Hiccup frequency, distress (Numerical Rating Scale [NRS] 0-10), and adverse events were evaluated. RESULTS: Three patients were excluded owing to aspiration during the practice session, and 19/41 who developed hiccups were analyzed. Median hiccup frequency decreased from 6.0 to 0.3 episodes/min. Median NRS scores decreased from 4.0 to 0. One patient experienced transient aspiration during FISST use. No serious adverse events occurred. CONCLUSION: The FISST may be a simple, self-administered option for CIH, warranting cautious use and further controlled evaluation.