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May 26, 2026BiomedicineOpen Access

Early life exposure to antibiotics increases the risk of myopia: a retrospective cohort study

Peng‐Tai Tien Chang‐Ching Wei Sheng-Chun Lin Ping Ping Meng Yu-Te Huang Jamie Jiin-Yi Chen Ming-Yen Wu Ying-Hsiu Shih Tzu-Ju Hsu Fuu-Jen Tsai Yao-Chien Wang Hui-Ju Lin Lei Wan

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Key Points

This study investigates the relationship between early life antibiotic exposure and the risk of developing myopia.
Retrospective cohort study using a national health insurance database
Included children aged three years or younger prescribed antibiotics
Matched case and control groups based on sex, age, and comorbidities.
Early antibiotic exposure significantly increases myopia risk (aHR=1.03, 95% CI=1.02–1.04)
Higher incidence rates observed in females (IR=66.98) and males (IR=61.53) compared to controls
Environmental factors independently influenced antibiotic exposure and myopia risk.

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Implication

Retrospective cohort study examines early antibiotic use and myopia risk in children, suggesting cautious prescribing practices.

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Cite This Study

Tien et al. (2026) studied this question.

synapsesocial.com/papers/6a192dd1fab5b468c4416c86 https://doi.org/10.37796/2211-8039.1666

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Time spent outdoors in childhood related to myopia among young adults in the Swedish ABIS cohort2024 · 7 citations
2Environmental antibiotics exposure and childhood obesity: A cross-sectional case-control study2024 · 11 citations
3Risk Factors in Childhood Myopia ProgressionOriginal Research · 2026
4Gene–environment Interactions in Childhood Myopia: Current Evidence and Future PerspectivesOriginal Research · 2026
5Lifestyle and environmental risk factors for myopia in children: Evidence from a large-scale cross-sectional study in Shandong, ChinaCross-Sectional Study · 2026 · 1 citations

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