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May 29, 2026Annals of the ICRP0 citations

Classification of harmful radiation-induced effects on human health for radiological protection purposes: history and concepts

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FZF. ZölzerLVL. VaillantLAL. Ainsbury

Key Points

  • The study aims to evaluate the classification of harmful radiation-induced health effects within the context of radiological protection.
  • Discussed historical and contemporary classifications of radiation effects as outlined by ICRP.
  • Analyzed implications of current scientific evidence on the existing classification system.
  • Considered the relevance of terminology used for radiation effects in radiological protection.
  • Identified the critical distinction between stochastic and deterministic effects for dose limit settings.
  • Highlighted the necessity for ongoing evaluation of classification system adequacy based on current evidence.
  • Suggested potential reevaluation of terminology surrounding 'deterministic effects' and 'tissue reactions'.

Abstract

The classification of harmful radiation-induced effects into 'stochastic' and 'deterministic' or 'cancer/heritable effects' and 'tissue reactions' has played a significant role in the recommendations of the International Commission on Radiological Protection (ICRP) over a number of decades. More recently, however, there has been a debate regarding the adequacy of the current scheme for classification of health effects with current scientific evidence. While these scientific aspects are discussed in greater detail in a parallel article, we will emphasise the practical importance of the classification itself here. The setting of dose limits is quite different for 'deterministic' and 'stochastic' effects. In the first case, provided reliable data regarding the threshold doses for radiation effects on a particular tissue are available, the dose limit is supposed to avoid harm altogether. With 'stochastic effects', the expected risks at the dose limit are supposed to be 'tolerable'. Below the dose limit, optimisation must be aimed for based on the 'prudent' assumption that the stochastic risks linearly depend on the dose and that there is no threshold. If the distinction between the two kinds of harmful effects is drawn into question, possible consequences for the system of radiological protection need to be considered, especially in the context of its aims as they currently apply, namely, 'to manage and control exposures to ionising radiation so that deterministic effects are prevented, and the risks of stochastic effects are reduced to the extent reasonably achievable'. It may be necessary, moreover, to discuss if and how the terminology used by ICRP (and others), in particular the terms 'deterministic effects' and 'tissue reactions', should continue to be used for the classification of radiation effects.

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Cite This Study

Zölzer et al. (2026) studied this question.

synapsesocial.com/papers/6a192e4efab5b468c441753fhttps://doi.org/10.1177/01466453251412089
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