Key result
Pharmacy-based single-lead ECG screening detects possible AF in ~2% of recordings despite limited clinical follow-up.
Why the study?
Sustainable community-based AF screening models that link results to medical evaluations are limited, despite opportunistic screening being advocated to prevent cardioembolic stroke.
Is a pharmacy-based atrial fibrillation screening model feasible and effective at linking detected cases to medical evaluation?
Observational (n=5,371)
Yes
Is a pharmacy-based atrial fibrillation screening model feasible and effective at linking detected cases to medical evaluation?
A pharmacy-based AF screening initiative is feasible for detecting possible AF, but significant gaps remain in linking patients to subsequent clinical evaluation.
Answers are grounded in this paper and cite their sources.
Pharmacy-based AF screening is feasible in community settings; leaves open whether it closes detection-to-treatment gaps or reduces stroke risk.
Background: Atrial fibrillation (AF) is a major cause of cardioembolic stroke and often remains undiagnosed because of its asymptomatic or paroxysmal nature. Although opportunistic AF screening has been advocated, sustainable community-based screening models that link the results to medical evaluations are limited. We implemented a pharmacy-based AF screening initiative (Catch AF project) led by a regional Stroke and Cardiovascular Disease Support Center with community pharmacists and physicians to assess its feasibility and follow-up outcomes. Methods and Results: The Catch AF project was conducted at 34 community pharmacies in Nagasaki, Japan. A single-lead electrocardiogram (ECG) device with automated analysis was installed to offer opportunistic screening for pharmacy visitors. Of the 5,371 ECG recordings, 123 (2.29%) indicated possible AF. Pharmacists recommended medical consultation for 60 individuals (49% of the detected cases). Questionnaire surveys demonstrated that stakeholders generally perceived the initiative as acceptable and feasible. In contrast, only a small number of physicians reported encounters with referred patients, indicating a marked gap between AF detection through pharmacy-based screening and subsequent medical evaluation. Conclusions: A center-led pharmacy-based AF screening initiative is feasible and well accepted in a real-world setting. However, a substantial gap between screening detection and clinical follow up highlights the need for improved referral pathways and coordination between pharmacies and medical institutions to enhance the effectiveness of community-based screening programs.
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Sakamoto et al. (2026) conducted an observational in Atrial fibrillation (n=5,371). Pharmacy-based AF screening (Catch AF project) was evaluated on Detection of possible atrial fibrillation. Pharmacy-based opportunistic screening using a single-lead ECG device detected possible atrial fibrillation in 2.29% of 5,371 recordings, though clinical follow-up was limited.
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