Key result
Orthostatic hypotension in older adults is linked to greater SBP drops during the sit-up test.
Why the study?
The sit-up test assesses orthostatic hypotension without a tilt table, but no studies had compared blood pressure responses between individuals with and without orthostatic hypotension during the test.
Does orthostatic hypotension detected by the sit-up test associate with altered blood pressure responses and poor health conditions in community-dwelling older adults?
Cross-Sectional (n=102)
Yes
Does orthostatic hypotension detected by the sit-up test associate with altered blood pressure responses and poor health conditions in community-dwelling older adults?
The sit-up test effectively identifies orthostatic hypotension in older adults, which is independently associated with poor health conditions such as comorbidities and frailty.
Answers are grounded in this paper and cite their sources.
Sit-up test detects orthostatic hypotension linked to altered BP responses and comorbidities in older adults; leaves open prospective validation before screening adoption.
Background The sit-up test enables the assessment of orthostatic hypotension without using a tilt table in individuals at high risk of falling when standing; however, no studies have compared blood pressure responses between those with and without orthostatic hypotension during this test. The primary objective of this study was to compare blood pressure responses during the sit-up test between community-dwelling older adults with and without orthostatic hypotension. The secondary objective was to determine the associations between orthostatic hypotension detected by the sit-up test and poor health conditions in these individuals. Methods One hundred-two community-dwelling older adults underwent the sit-up test. Orthostatic hypotension was defined as a decrease of ≥10 mmHg in systolic blood pressure and/or ≥5 mmHg in diastolic blood pressure during the test. Supine and seated hypertension were evaluated, defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Blood pressure responses during the test were compared between participants with and without orthostatic hypotension. Moreover, associations of orthostatic hypotension with demographic, clinical, and geriatric outcomes were examined. Results Thirty-four participants (33.3%) showed orthostatic hypotension during the test. Participants with orthostatic hypotension demonstrated a greater decrease in systolic blood pressure (F (3,297) = 47.0, p < 0.001), a smaller increase in diastolic blood pressure (F (3,297) = 26.5, p < 0.001), and higher supine systolic blood pressure (t = 3.363, p = 0.005) during the test than those without orthostatic hypotension. Consequently, 52.9% of participants with orthostatic hypotension had supine hypertension. Orthostatic hypotension was associated with a higher proportion of participants with at least one comorbidity (odds ratio = 4.50, p = 0.002) and those with non-robust status (odds ratio = 3.08, p = 0.022), even after adjusting for supine and seated hypertension. Conclusion Community-dwelling older adults with orthostatic hypotension were characterized by an impaired orthostatic increase in diastolic blood pressure and high supine systolic blood pressure during the sit-up test. Orthostatic hypotension was associated with poor health conditions, independently of supine and seated hypertension. These findings contribute valuable insights for the application of the sit-up test in preventive health screenings for older adults.
No takes yet. Share an insight, caveat, or question.
Oyake et al. (2025) conducted a cross-sectional in Orthostatic hypotension (n=102). Orthostatic hypotension (detected by sit-up test) vs. No orthostatic hypotension was evaluated on Decrease in systolic blood pressure during the sit-up test (p=<0.001). Community-dwelling older adults with orthostatic hypotension demonstrated a significantly greater decrease in systolic blood pressure and a smaller increase in diastolic blood pressure during the sit-up test.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: