Key result
Middle-age occupational physical activity linked to a ~2 mmHg higher standing SBP response.
Why the study?
Orthostatic hypotension is common in older people, motivating an examination into the influence of self-reported occupational-related physical activity and leisure-time physical exercise on orthostatic response over a 2-year period.
Does a history of occupational and leisure-time physical activity in middle age prevent orthostatic blood pressure decline in older adults?
Cohort (n=205)
No
Does a history of occupational and leisure-time physical activity in middle age prevent orthostatic blood pressure decline in older adults?
Effect estimate: 2.34 mmHg increase
p-value: p=0.03
Occupational and leisure-time physical activity during middle age may protect against orthostatic blood pressure declines in older adulthood.
May suggest midlife activity benefits orthostatic responses but should not change practice; leaves open causal protection against hypotension.
Orthostatic hypotension (OH) is common in older people. We examined the influence of self-reported occupational-related physical activity (PA) and leisure-time physical exercise (PE) on orthostatic response in a sample of older people over a 2 year period. Supine and orthostatic systolic blood pressure (sBP), diastolic blood pressure (dBP), and mean blood pressure (mBP) were assessed in response to Active Stand (AS) test in 205 older subjects (> 60 years old) at baseline and 2-year follow-up. OH was found in 24 subjects (11.71%) at baseline and 20 subjects (9.76%) after 2 years, with a significant degree of variability in the occurrence of OH after 2 years. Twenty-two subjects who had OH at baseline were free of it after 2 years, two subjects had persistent OH at baseline and after 2 years. After 2 years, adults with occupational PA showed no significant decrease of blood pressure in response to AS test, while lack of undertaking an occupation-related PA was significantly related with a greater decrease in sBP and mBP in response to AS testing in the 1st min. Occupation-related PA and leisure-time-related PE were related to an increase in the response of BP on AS in change between baseline and after 2 years. High between-subjects variance in OH over 2 years was noted. Occupations that involved continuous physical activity and leisure-time physical exercise in middle age were both protective for BP decline on orthostatic stress test within 2 years.
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Kujawska et al. (2023) conducted a cohort in Orthostatic hypotension (n=205). Occupational-related physical activity and leisure-time physical exercise vs. No occupational-related physical activity or leisure-time physical exercise was evaluated on Change in 1st minute systolic blood pressure (sBP) response to Active Stand test over 2 years (2.34 mmHg increase, p=0.03). Occupational-related physical activity in middle age was associated with a 2.34 mmHg increase in 1st minute systolic blood pressure response to active standing over a 2-year period in older adults.
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