Key result
HIV-infected veterans with a pulmonary artery systolic pressure ≥40 mm Hg had a significantly increased risk of death compared to uninfected veterans with normal pressure (HR 1.78).
Why the study?
Does HIV infection and increased pulmonary artery systolic pressure increase mortality in veterans referred for echocardiography?
Observational (n=8,296)
Yes
Does HIV infection and increased pulmonary artery systolic pressure increase mortality in veterans referred for echocardiography?
HIV-infected veterans have a higher prevalence of increased pulmonary artery systolic pressure, which is associated with a significantly increased risk of mortality even at values currently considered normal.
Answers are grounded in this paper and cite their sources.
Elevated PASP signals higher mortality risk in HIV veterans; leaves open whether screening or intervention alters outcomes.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Brittain et al. (2017) conducted an observational in HIV infection and pulmonary hypertension (n=8,296). HIV infection with increased pulmonary artery systolic pressure (≥40 mm Hg) vs. HIV-uninfected with normal pulmonary artery systolic pressure (<40 mm Hg) was evaluated on All-cause mortality (HR 1.78, 95% CI 1.57-2.01). HIV-infected veterans with a pulmonary artery systolic pressure ≥40 mm Hg had a significantly increased risk of death compared to uninfected veterans with normal pressure (HR 1.78).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: