“Inside CKD” Multinational-Microsimulation Modelling Insights Into the Increasing CKD Burden

Introduction: Chronic kidney disease (CKD) affects approximately 1 in 10 people worldwide and is associated with increased morbidity and mortality, yet it remains underdiagnosed, undertreated, and underrecognized compared with other noncommunicable diseases. Methods: from 31 countries and regions, in the context of existing guidelines, recommendations, and other global initiatives. Results: Our findings highlight that, if current low rates of diagnosis are maintained, the CKD population is projected to increase by 5.8%, with associated health care costs increasing by 9.3%, by 2027. Screening for CKD is also projected to be cost-effective and to modestly increase life expectancy. Conclusion: Implementing screening and treatment strategies will be crucial for the early identification of CKD and for overcoming the current clinical inertia around the diagnosis and management of CKD.