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Introduction. Simple Comparison Experiments. Two Factors, Each at Two Levels. Two Factors, Each at Three Levels. Unreplicated Three--Factor, Two--Level Experiments. Unreplicated Four--Factor, Two--Level Experiments. Three Five--Factor, Two--Level Unreplicated Experiments. Larger Two--Way Layouts. The Size of Industrial Experiments. Blocking Factorial Experiments, Fractional Replication--Elementary. Fractional Replication--Intermediate. Incomplete Factorials. Sequences of Fractional Replicates. Trend--Robust Plans. Nested Designs. Conclusions and Apologies.
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Weisberg et al. (1978) studied this question.
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