What question did this study set out to answer?

Characterize diagnostic biomarkers and evaluate the clinical efficacy of thyroid replacement therapy in progressive autoimmune thyroid gland destruction.

October 1, 1964Archives of Disease in ChildhoodOpen Access

Paediatric Aspects of Cerebral Palsy

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Implication

Review reports elevated antibody titres and iodine markers in thyroid disease, suggesting dried thyroid extract therapy prevents progressive gland destruction.

Key Points

Characterize diagnostic biomarkers and evaluate the clinical efficacy of thyroid replacement therapy in progressive autoimmune thyroid gland destruction.
Evaluated serological profiles using haemagglutinating and complement-fixing antibody techniques.
Measured circulating protein-bound iodine and butanol extractable iodine concentrations alongside responses to dried thyroid extract regimens.
Elevated haemagglutinating and complement-fixing titres, alongside raised protein-bound and butanol extractable iodine levels, served as characteristic diagnostic indicators.
Administration of dried thyroid extract for at least two years provided an effective therapeutic regimen against potential complete destruction of the thyroid gland.

Cite This Study

A 1964 study studied this question.

synapsesocial.com/papers/6a196f9ff2eb401dc789166c https://doi.org/10.1136/adc.39.207.529-a

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Implication

Review reports elevated antibody titres and iodine markers in thyroid disease, suggesting dried thyroid extract therapy prevents progressive gland destruction.

Paediatric Aspects of Cerebral Palsy

Discussion

Member takes

Implication

Key Points

Cite This Study

Paediatric Aspects of Cerebral Palsy

Discussion

Member takes

Implication

Key Points

Cite This Study

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