Associations Between Age and Resting State Connectivity Are Partially Dependent Upon Cardiovascular Fitness

Figures

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  FIGURE 1. (A) Scatterplot of frontoparietal control network (FPCN) connectivity by self-reported age in years. (B) Scatterplot of default mode network (DMN) connectivity by self-reported age in years.

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  FIGURE 2. (A) Sagittal, transverse, and coronal images displaying functional connections between ROIs within the FPCN that were significantly different in terms of strength between young and older adults and passed correction for false discovery rate; blue connections indicate stronger functional connectivity among young adults, while red connections indicate stronger functional connectivity among older adults. Note that in this analysis there were no connections that were stronger in older adults. (B) Sagittal, transverse, and coronal images displaying functional connections between ROIs within the FPCN that were significantly different in terms of strength between young and older adults when controlling for VO2 peak and passed correction for false discovery rate; blue connections indicate stronger functional connectivity among young adults, while red connections indicate stronger functional connectivity among older adults. Note that in this analysis there were no connections that were stronger in older adults.

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  FIGURE 3. (A) Sagittal, transverse, and coronal images displaying functional connections between ROIs within the DMN that were significantly different in terms of strength between young and older adults and passed correction for false discovery rate; blue connections indicate stronger functional connectivity among young adults, while red connections indicate stronger functional connectivity among older adults. (B) Sagittal, transverse, and coronal images displaying functional connections between ROIs within the DMN that were significantly different in terms of strength between young and older adults when controlling for VO2 peak and passed correction for false discovery rate; blue connections indicate stronger functional connectivity among young adults, while red connections indicate stronger functional connectivity among older adults.