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What are the long-term clinical outcomes and functional status in children following an episode of infective endocarditis?
What are the long-term clinical outcomes and functional status in children following an episode of infective endocarditis?
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Children who survive infective endocarditis generally maintain good functional status long-term, despite a risk of late deaths, recurrences, and intracardiac sequelae.
A follow-up study on 36 children having had infective endocarditis during the time period 1971-80 was performed. All answered a questionnaire and 33 underwent a complete non-invasive cardiac examination including exercise test. The study comprised 406 patient years. During this time there were four late deaths and three recurrent attacks of endocarditis. Seventeen (47%) took prophylactic antibiotics. Two patients had been operated on because of the initial infection and another five had developed intracardiac sequelae. An ability index given to each patient before the infection and at the follow-up showed that as a group these patients were doing well.
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Schollin et al. (1989) studied this question.
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