Increasing MeCP2 protein in Pitt-Hopkins syndrome model (Tcf4+/−) mice does not affect abnormal myelination but induces the generation of astrocytes

mice in the presence of the MECP2 transgene, as well as the presence of cells with astrocytic morphology in the brains of these animals, suggesting a potential interplay of MeCP2 and TCF4 in astrocyte development.