Electroencephalographic changes of panic disorder patients in west Uttar Pradesh

80 panic disorder patients were diagnosed with electroencephalography (EEG). The study was electroencephalographic (EEG) changes of Panic Disorder patients in West Uttar Pradesh,India. The objectives 1) To examine the EEG of Panic Disorder patients. 2)To explore the clinical features for the diagnosis of panic disorder and their association with EEG. A large group of patients having panic disorder showed abnormal EEG associated with their clinical features. The pathophysiology behind is not clarified. The study was interpreted with 14 (17.5%) panic disorder patients and EEG abnormalities of 80 patients conflict with 13 symptoms in DSM-IV. The patients were assessed with Logistic regression analysis.EEG was selected as the dependent variable and age, sex, and with or without 13 symptoms as independent variables. The panic disorder patients showed abnormal EEG alpha frequency with repeatedly slow theta frequency. Nausea or abdominal distress (43.4% vs 67.7%, p = 0.01); derealization or depersonalization (37.7 %vs82.4%, p = 0.005); or paresthesias (7.5%vs47.1%, p = 0.001) were extracted by multivariate analysis as factors related to EEG abnormalities. The study indicated that physiological predispositions are closely related to panic disorder.