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Renewal SS-cream is a topical agent modified from the original SS-cream which is effective in the treatment of premature ejaculation. In this study, the efficacy of renewal SS-cream on premature ejaculation caused by the bulbocavernosus reflex (BCR) was investigated in rabbits. Sixty male New Zealand white rabbits (weights: 2.5∼3.0 kg) were divided into 3 groups randomly. Either renewal or original SS-cream or placebo (provided by CJ Co. LTD) was topically applied to the glans penis of rabbits in a double-blind manner. The bulbocavernosus reflex (BCR) was elicited by electrical stimulation of the glans penis. The latency of BCR (BCRLT) and the amplitude of BCR (BCRAP) were recorded on an electrophysiograph (Poseidomn, Shanghai, China) before and at 10, 30 and 60 min after application of the test agents.
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Tian et al. (2008) studied this question.
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