Why the study?
Does polycystic ovary syndrome increase the risk of coronary and aortic calcification in middle-aged women?
Population
146 middle-aged women, comprising 61 with polycystic ovary syndrome (PCOS) and 85 similarly aged controls
Comparison
Polycystic ovary syndrome (PCOS) as an exposure vs Similarly aged controls without PCOS
Design
Cohort
Follow-up
9 years
Authors
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May inform risk stratification in PCOS; extends metabolic observations but leaves event risk open.
Does polycystic ovary syndrome increase the risk of coronary and aortic calcification in middle-aged women?
Women with PCOS have an increased risk of metabolic cardiovascular syndrome and demonstrate a higher prevalence of coronary and aortic calcification compared to controls, independent of obesity.
Talbott et al. (2004) studied this question.
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