Key result
Changes in short-interval intracortical inhibition during fatiguing exercise were only detectable with transcranial magnetic stimulation intensities evoking maximal responses.
Why the study?
Does TMS intensity (maximal vs submaximal) affect the detectability of changes in SICI and SP during fatiguing exercise?
Does TMS intensity (maximal vs submaximal) affect the detectability of changes in SICI and SP during fatiguing exercise?
When measuring short-interval intracortical inhibition during fatiguing exercise, it is important to use TMS intensities that evoke maximal responses to detect changes.
Submaximal TMS intensities may miss SICI changes during exercise; leaves open standardization of protocols for fatigue research.
This study compared the change in silent period (SP) and short-interval intracortical inhibition (SICI) with conditioning stimulus and single-pulse transcranial magnetic stimulation (TMS) intensities (for SICI and SP, respectively) eliciting maximal and submaximal SICI and SP during fatiguing exercise. The results showed that changes in SICI were only detectable with intensities evoking maximal responses, with no difference between intensities for SP. These findings highlight the importance of maximizing SICI with appropriate intensities before measuring SICI during fatiguing exercise.
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Brownstein et al. (2020) studied this question. Transcranial magnetic stimulation intensities evoking maximal responses vs. Intensities evoking submaximal responses was evaluated on Change in silent period (SP) and short-interval intracortical inhibition (SICI). Changes in short-interval intracortical inhibition during fatiguing exercise were only detectable with transcranial magnetic stimulation intensities evoking maximal responses.
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