Geroscience and the Role of Aging in the Etiology and Management of Alzheimer's Disease

With the relentless aging of the population worldwide, two major concerns need our immediate attention: the expected dramatic increase in disease and disability burden, and the decrease in the ratio of working individuals vs. retirees. A comprehensive approach involving experts in many disciplines will be required to tackle these issues. Here we will concentrate on the role of basic biological science in averting the increase in disease and disability, using Alzheimer’s Disease (AD) as a model.