Anti-Xa assays lack large randomized controlled trials correlating them with clinical outcomes, leaving the optimal method for monitoring intravenous unfractionated heparin therapy unknown.
What is the role of anti-Xa assays in monitoring intravenous unfractionated heparin therapy?
This review highlights the clinical applications of anti-Xa assays for heparin monitoring while noting the absence of large randomized controlled trials to definitively establish the best monitoring method.
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Although some suggest anti-Xa assays should be the preferred method for monitoring intravenous unfractionated heparin therapy, which method is best is unknown owing to the lack of large randomized controlled trials correlating different assays with clinical outcomes. This article provides an overview of heparin monitoring and the pros, cons, and clinical applications of anti-Xa assays.
Hutt et al. (Sat,) reported a other. Anti-Xa assays lack large randomized controlled trials correlating them with clinical outcomes, leaving the optimal method for monitoring intravenous unfractionated heparin therapy unknown.