Key result
TCD and ultrasound evaluations standardize cerebral and extracerebral hemodynamic parameters in healthy children.
Why the study?
Normal pediatric cerebral blood flow parameters are often evaluated using small groups, adult data, or neurological hospital cohorts, even though hemodynamics differ in children aged 1 to 18 years.
Observational (n=10,000)
This large-scale observational study establishes normative data and standardizes protocols for cerebral and extracerebral hemodynamics using ultrasound in children aged 1 to 18 years.
Ultrasound methods of radiation diagnostics are one of the main screening methods in the algorithm of management of patients with cerebrovascular disoders. As a rule, the results of examination of children are evaluated in literature either in small groups (up to 20 healthy children), or in accordance with the data of adult patients. There is also a comparison with the results of examination of patients from neurological hospital, represented by the “norm” (H. Bode, 1985–1986). However, blood flow parameters may not be the same in children aged 1 to 18 years and in older patients. And even small deviations can affect the physical and psycho-emotional development of the child and cause vascular catastrophes. Over the course of 25 years, more than 10,000 children aged 1 to 18 years have been examined. The main parameters of cerebral and extracerebral hemodynamics have been determined, TCD and ultrasound study protocols for children have been standardized.
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Abramova et al. (2025) conducted an observational in Healthy children (n=10,000). Ultrasound methods (TCD and ultrasound study protocols) was evaluated on Main parameters of cerebral and extracerebral hemodynamics. Over 25 years, more than 10,000 healthy children aged 1 to 18 years were examined to determine the main parameters of cerebral and extracerebral hemodynamics and standardize ultrasound protocols.
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