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April 15, 2015Marmara Medical JournalOpen Access

What to expect from HER-2 directed therapies in advanced gastric cancer?

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Abstract

Gastric cancer is the second most common cause of cancer related death worldwide. Over 20% of the advanced gastric cancer are considered to be HER-2 positive. Studies investigating the prognosis of HER-2 positive advanced gastric cancer revealed conflicting results. Trastuzumab, a monoclonal antibody against HER-2, has shown a significant clinical activity in HER-2 positive gastric cancer patients. In this review, I will briefly summarize the clinical studies of anti-HER-2 therapies performed in HER-2 positive gastric carcinoma.

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Cite This Study

Faysal Dane (2015) studied this question.

synapsesocial.com/papers/6a1a22d4d76fa4bea136fffb https://doi.org/10.5472/mmj.87204

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