Why the study?
Do coronary interventional techniques (angioplasty and stenting) improve outcomes compared to thrombolytic therapy in patients with acute myocardial infarction?
Do coronary interventional techniques (angioplasty and stenting) improve outcomes compared to thrombolytic therapy in patients with acute myocardial infarction?
Mechanical reperfusion via coronary angioplasty and stenting may offer significant advantages over thrombolytic therapy for acute myocardial infarction.
Does not yet warrant changing reperfusion strategies in acute MI; leaves open the need for randomized trials of mechanical versus thrombolytic approaches.
Despite the improvements in the pharmacological treatment of acute myocardial infarction, it is recognised that thrombolysis fails to reproduce reperfusion in a significant proportion of patients. Coronary interventional techniques have been shown to offer an alternative reperfusion strategy. There is increasing evidence that mechanical reperfusion may offer significant advantages over established thrombolytic therapy.
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Brodison et al. (1999) studied this question.
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