Why the study?
Coronary artery disease is a significant cause of illness and death in women, but sex differences in pathophysiology, manifestations, and outcomes remain under-recognized.
This review emphasizes the under-recognized sex differences in the pathophysiology, presentation, and outcomes of coronary artery disease in women.
May warrant sex-specific CAD assessment in women; leaves open dedicated prospective trials to guide management.
Coronary artery disease (CAD) is a significant cause of illness and death amongst women. The pathophysiology, manifestations, and outcomes of CVD and CAD differ between sexes. These sex differences remain under-recognized. The aim of this review is to highlight and raise awareness of the burden and unique aspects of CAD in women. It details the unique pathophysiology of CAD in women, cardiovascular risk factors in women (both traditional and sex-specific), the clinical presentation of CAD in women, and the range of disease in obstructive and non-obstructive CAD in women.
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Pravda et al. (2021) studied this question.
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