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dramatic fall in the parasitaemia to 0-5%.Forty eight hours after admission her temperature was normal and no parasites were detectable in further films.The quinine was then continued orally for 10 days at a dose of 600 mg every 12 hours.Her subsequent antenatal course was uncomplicated.Films remained negative for malarial parasites.Four weeks after her admission she was readmitted in spontaneous labour that resulted in a vaginal delivery of a healthy girl weighing 2680 g.The puerperium was uneventful.* Distributed between year 1 (3 patients), year 2 (7), year 3 (3), year 4 (1), and year 5 (2).
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Holton et al. (1990) studied this question.
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