SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier Dysfunction

Stefanie Deinhardt‐Emmer; Sarah Böttcher; C. M. Haring; Liane N. Giebeler; Andreas Henke; Roland Zell; Johannes Jungwirth; Paul M. Jordan; Oliver Werz; Franziska Hornung; Christian Brandt; Mike Marquet; Alexander S. Mosig; Mathias W. Pletz; Michael Schacke; Jürgen Rödel; Regine Heller; Sándor Nietzsche; Bettina Löffler; Christina Ehrhardt

doi:10.1128/jvi.00110-21

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Abstract

experiments, but we were able to show the destruction of the epithelial-endothelial barrier in our chip model. From our experiments we can assume that virus-induced host factors disturbed the epithelial-endothelial barrier function and thereby promote viral spread.

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Deinhardt‐Emmer et al. (2021) studied this question.

synapsesocial.com/papers/6a1a546e3f4a8d1a389bbeac https://doi.org/10.1128/jvi.00110-21

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SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier Dysfunction

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SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier Dysfunction

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