Cardiac surgery presents a major pro-inflammatory stimulus, and understanding pre- and intraoperative factors is important for maintaining cytokine balance.
May inform strategies to maintain cytokine balance in cardiac surgery; leaves open whether modulation improves outcomes.
Homeostatic control of the balance of pro- and anti-inflammatory cytokines is important for the maintenance of health. Cardiac surgery, with its intense pro-inflammatory stimulus, constitutes a major challenge to the patient's ability to maintain this balance. Pre- and intraoperative factors influencing the maintenance of cytokine balance are discussed.
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McBride et al. (1998) studied this question.