Why the study?
Does 30 days of 6 degrees head-down bed rest impair vagal baroreflex responses and provoke orthostatic hypotension in healthy men?
Population
11 healthy men
Comparison
30 days of 6 degrees head-down bed rest vs Control measurements before bed rest
Design
Cohort
Follow-up
30 days of bed rest and 5 days of recovery
Authors
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May contribute to orthostatic intolerance after simulated microgravity; leaves open whether countermeasures can restore vagal baroreflex function.
Does 30 days of 6 degrees head-down bed rest impair vagal baroreflex responses and provoke orthostatic hypotension in healthy men?
Head-down bed rest simulating microgravity impairs vagal baroreflex responses, which correlates with the development of orthostatic hypotension upon standing.
Convertino et al. (1990) studied this question.