Ascher Syndrome – A Rare Case Report

Ascher syndrome, also referred to as Laffer–Ascher syndrome, is an infrequent and non-malignant dermatological condition marked by a classic set of three hallmark signs: An extra fold of the upper lip, drooping of the upper eyelids and thyroid enlargement unlinked to excess hormone activity. Not all individuals exhibit thyroid involvement, and such cases are categorised as the incomplete or forme fruste variant. The disorder may have a developmental origin or be acquired later due to repetitive trauma or oral habits. Initial symptoms often include brief episodes of symmetrical swelling in the upper eyelids, eventually progressing into blepharochalasis. Medical treatments – such as corticosteroids, antihistamines and dapsone – offer limited benefit. Surgical intervention may be considered in instances where visual function, speech, chewing ability or eye health is compromised.