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May 9, 2026Experimental Cell ResearchOpen Access

The redox-active CXXC motif of BCAT1 regulates extracellular vesicle biogenesis in U937 macrophages

James Hillier Mathieu Brunet Rebecca Terry Joanne Whittaker Gemma Allcot Sophie C. Cox Patricia Esteban Steven J. Coles Ivan Wall

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Abstract

EV abundance. Taken together, these data indicate that BCAT1, and its redox-active CXXC motif, may play a novel role in EV biogenesis in macrophage-like cells.

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Hillier et al. (2026) studied this question.

synapsesocial.com/papers/6a1a8fb78198c9a8aa45d55a https://doi.org/10.1016/j.yexcr.2026.115049

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