Gut microbial composition and diversity varies by CREBRF genotype among Samoan infants

This is the authors' abstract. We don't add key points for this paper.

Missense variant rs373863828 in CREBRF is associated with higher odds of obesity but lower odds of diabetes among Polynesians. We examined associations between CREBRF genotype and gut microbial diversity and composition among Samoan infants and identified significant differences at age 21 mo but not at age 0 or 4 mo. These results suggest that gut microbiota may contribute to the mechanisms through which CREBRF genotype impacts metabolic health.