Why the study?
Does rivaroxaban resolve right atrial thrombosis resistant to warfarin in a patient with atrial fibrillation?
Does rivaroxaban resolve right atrial thrombosis resistant to warfarin in a patient with atrial fibrillation?
Rivaroxaban may be an effective alternative for resolving right atrial thrombosis that is resistant to standard warfarin therapy in patients with atrial fibrillation.
Answers are grounded in this paper and cite their sources.
Rivaroxaban may resolve warfarin-resistant right atrial thrombosis in AF; hypothesis-generating and requires prospective trials.
A 72-year-old man with non-valvular atrial fibrillation and metastatic liver and lung cancer after surgery for colon cancer developed thrombosis in the right atrium one month after decreasing the dose of warfarin due to the introduction of double anti-platelet therapy for coronary stent implantation. Restoring the warfarin dose with ordinary control for two months did not result in any changes in the size of the thrombus; however, the subsequent substitution of rivaroxaban (oral treatment with a direct Factor Xa inhibitor) for warfarin ultimately resolved the thrombosis.
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Kawano et al. (2015) studied this question.
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