Key result
Very severe hypertriglyceridemia (triglycerides >10,000 mg/dL) presented in a 46-year-old female without evidence of acute pancreatitis, highlighting a rare clinical presentation.
Why the study?
Cases of very severe hypertriglyceridemia without evidence of acute pancreatitis are very rare.
Case Report (n=1)
This case highlights a rare presentation of very severe hypertriglyceridemia (>10,000 mg/dL) without acute pancreatitis in a patient with a history of hypertriglyceridemia-induced pancreatitis.
Clinicians should consider very severe hypertriglyceridemia even absent pancreatitis; this case leaves open questions on risk thresholds and atypical presentations.
A 46-year-old female presents to the emergency department with very severe hypertriglyceridemia (HTG) with a total triglyceride (TG) count over 10,000 mg/dL with no evidence of acute pancreatitis. There have been very few cases of very severe hypertriglyceridemia without evidence of acute pancreatitis, based on literature review. It is also rare for triglyceride (TG) counts to exceed 2000 without an underlying genetic cause. Monogenic causes of HTG are uncommon and the true cause of HTG is usually multifactorial. Treatment of severe HTG such as this case often involves long-term lifestyle and dietary modifications.
No takes yet. Share an insight, caveat, or question.
Guerriero et al. (2021) conducted a case report in Severe hypertriglyceridemia (n=1). Lifestyle and dietary modifications was evaluated. Very severe hypertriglyceridemia (triglycerides >10,000 mg/dL) presented in a 46-year-old female without evidence of acute pancreatitis, highlighting a rare clinical presentation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: