Key result
Contemporary imaging techniques help define diabetic cardiomyopathy and understand its pathophysiologic mechanisms, though prospective evidence for early detection preventing morbidity is lacking.
This review highlights the current understanding of diabetic cardiomyopathy pathophysiology and discusses contemporary imaging methods and their limitations.
Imaging refines diabetic cardiomyopathy phenotyping; leaves open whether early detection improves outcomes.
Diabetic cardiomyopathy is recognized as a distinct disease entity characterized by left ventricular dysfunction in absence of hypertension or coronary artery disease, and independent of glucose control. Early detection may be particularly important for preventing cardiovascular morbidity and mortality, but prospective evidence for this approach is lacking. The pathophysiology of diabetic cardiomyopathy does not remain completely understood. Besides several animal models, contemporary imaging techniques have helped not only to define this clinical entity, but to also understand pathophysiologic mechanisms. This review aims to highlight the current understanding of the disease process and to discuss current imaging methods and their limitations.
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Hawi et al. (2014) conducted a review in Diabetic cardiomyopathy. Imaging methods was evaluated. Contemporary imaging techniques help define diabetic cardiomyopathy and understand its pathophysiologic mechanisms, though prospective evidence for early detection preventing morbidity is lacking.
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