Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.
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Liu et al. (2003) studied this question.
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