Key result
Elevated HARMS2-AF score predicts POAF after isolated CABG with ~91% sensitivity.
Why the study?
Postoperative atrial fibrillation is a common complication after cardiac surgery, but the ability of previous risk scores to accurately identify patients at risk remains limited.
Does the HARMS2-AF score predict postoperative atrial fibrillation in patients undergoing isolated CABG surgery?
Cohort (n=265)
No
Does the HARMS2-AF score predict postoperative atrial fibrillation in patients undergoing isolated CABG surgery?
Effect estimate: AUC 0.787 (95% CI 0.731-0.842)
p-value: p=<.001
BACKGROUND: Postoperative atrial fibrillation (POAF) remains a common complication after cardiac surgery. The ability to accurately identify patients at risk through previous risk scores is limited. This study aimed to evaluate the new HARMS2-AF risk score to predict POAF after coronary artery bypass grafting (CABG) surgery. METHODS: In this retrospective cohort study, we included 265 patients undergoing CABG surgery from 2022-2023. Data were obtained from the medical files of the patients and hospital records. Each patient was assigned a HARMS2-AF risk score. A univariate and multivariate regression analyses were done to analyze independent predictors of POAF. RESULTS: Of 265 patients, 49 had postoperative atrial fibrillation. HARMS2-AF score was significantly higher in patients with POAF. Age, sleep apnea,a left atrial diameter (LAd), and HARMS2-AF score were independently associated with POAF. A HARMS2-AF score ≥ 4.5 predicted POAF with 91% sensitivity and 64% specificity (AUC = 0.787, 95% CI = 0.731-0.842, P < .001). CONCLUSION: The HARMS2-AF score is a strong predictor of atrial fibrillation (AF) development after isolated CABG surgery. It can be used as a novel stratification tool to estimate AF after cardiac surgery.
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Can Ramazan Öncel (2024) conducted a cohort in Postoperative atrial fibrillation (POAF) (n=265). HARMS2-AF score was evaluated on Postoperative atrial fibrillation (AUC 0.787, 95% CI 0.731-0.842, p=<.001). A HARMS2-AF score ≥ 4.5 predicted postoperative atrial fibrillation after isolated CABG surgery with 91% sensitivity and 64% specificity (AUC 0.787).
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