Key result
Surgical repair of asymptomatic severe mitral regurgitation in Centers of Excellence achieves >95% success with <1% mortality, while transcatheter chordal repair emerges for high-risk patients.
Why the study?
In degenerative mitral regurgitation, surgical repair is the standard of care, but emerging transcatheter chordal replacement devices are providing therapeutic options for high-risk patients.
Transcatheter chordal replacement devices are emerging as a viable therapeutic option for high-risk patients with degenerative mitral regurgitation.
Supports referral to valve centers for asymptomatic severe MR; leaves open transcatheter chordal repair's role pending prospective trials.
The field of mitral valve disease diagnosis and management is rapidly evolving.New understanding of pathophysiology and improvements in the adoption of sophisticated multimodality imaging modalities have led to early diagnosis and to more complex treatment.The most common cause of mitral regurgitation (MR) in the western world is in the primary alteration of the valve, which leads to degenerative leaflet prolapse due to chordal elongation or rupture and annular dilatation.Untreated, significant MR has a negative impact prognosis, leading to reduction of survival.In the setting of degenerative MR, surgical repair currently represents the standard of care.Treatment of asymptomatic patients with severe MR in the Valve Center of Excellence, in which successful repair reaches more than 95% and surgical mortality less than 1%, symbolizes the direction for the next years.Transcatheter mitral valve repair with different devices, more recently the chordal replacement ones, is providing good outcomes and became a therapeutic option in highrisk patients with degenerative MR.In the future, more advances are expected from further development of interventional techniques, careful evaluation and better patient selection.This review will focus on long-term surgical outcomes of mitral valve repair with artificial chordae and on the emerging transcatheter chordal repair devices as therapeutic options for degenerative MR patients.
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Savić et al. (2018) conducted a review in Degenerative mitral regurgitation. Transcatheter mitral valve chord repair was evaluated. Surgical repair of asymptomatic severe mitral regurgitation in Centers of Excellence achieves >95% success with <1% mortality, while transcatheter chordal repair emerges for high-risk patients.
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