Key result
Spontaneous coronary artery dissection is an important differential diagnosis of acute coronary syndrome, particularly in young women, though uncertainties remain regarding its optimal management.
Why the study?
Many uncertainties remain regarding the pathophysiology, risk factors, acute treatment, and optimal long-term management of spontaneous coronary artery dissection.
This review summarizes current scientific evidence on the epidemiology, management, and outcomes of spontaneous coronary artery dissection, an important differential diagnosis of acute coronary syndrome.
SCAD merits consideration in young women with ACS; leaves optimal management unresolved for prospective trials.
Spontaneous coronary artery dissection is an infrequent cause of acute coronary syndrome with comparable clinical features. Previously considered a rare disease, recent scientific interest has revealed spontaneous coronary artery dissection as an important differential diagnosis of acute coronary syndrome, especially in young women, during pregnancy or postpartum, and in patients with fibromuscular dysplasia or other arteriopathies. However, there remain many uncertainties regarding pathophysiology, risk factors, acute treatment, and optimal long-term management. The aim of this review is to summarize current scientific evidence on epidemiology, management, and outcomes.
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Würdinger et al. (2021) conducted a review in Spontaneous coronary artery dissection. Spontaneous coronary artery dissection is an important differential diagnosis of acute coronary syndrome, particularly in young women, though uncertainties remain regarding its optimal management.
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